What Are Some Brand Names of DPP-4 Inhibitors?


Quick Answer

Brand names for dipeptidyl peptidase-4 inhibitors include Nesina, Tradjenta, Onglyza and Januvia, according to WebMD. These medicines treat type 2 diabetes, and patients often take them in combination with other medications.

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Full Answer

Dipeptidyl peptidase-4, or DPP-4, inhibitors help maintain a desired blood sugar level in people with type 2 diabetes, reports WebMD. They work by preventing the DPP-4 enzyme from removing incretin, a hormone that triggers the release of insulin in the body. Some people with type 2 diabetes produce low levels of incretin, and by preventing DPP-4 from removing it, the amount that does get produced remains for a longer period, allowing it to stimulate the production of insulin and help lower blood sugar levels.

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