Bronchiolitis obliterans with organizing pneumonia, or BOOP, is inflammation and clogging of the bronchioles, alveoli and the small bronchi walls with connective tissue, according to Mayo Clinic. This condition only occurs in rare cases.
BOOP results from multiple causes including inflammatory disorders, transplanted tissues and exposure to drugs and cancer treatments such as radiology and chemotherapy, explains Mayo Clinic. The inflammatory disorders that predispose an individual to BOOP include rheumatoid arthritis and lupus. In some cases, individuals who undergo tissue transplant such as a bone marrow or lung transplant are more likely to develop BOOP. Other tissue transplants that may result in BOOP include stem cell or kidney transplants. Additionally, individuals who consume drugs such as cocaine, gold salts and medications that treat seizure are also at a higher risk of developing BOOP.
Although not all BOOP patients experience symptoms, BOOP often results in a continuous nonreproductive cough among patients, states Mayo Clinic. It may also lead to breath shortness depending on the extent of the lung damage. BOOP can be treated by use of steroids or by addressing the causing infection, and the recovery period can last from weeks to months. However, the treatment of BOOP does not guarantee improvement in all patients.