There is little reputable, independent evidence of the effectiveness of BioTrust IC-5, and the existing evidence is contradictory. For example, BioTRUST is a Better Business Bureau accredited business, according to the bureau's website. However, as of 2015, there is no independent evidence that proves its effectiveness, notes Consumer Health Digest.
BioTRUST IC-5 contains cinnamon bark, berberis aristata root bark extract, pterocarpus marsupium, fenugreek extract and r-alpha lipoic acid, according to the company website.
The effect of cinnamon bark on blood sugar has been more widely studied in animals than in humans, as of 2015, according to Healthline. However, a few studies that have investigated the link show better blood sugar control in Type 2 diabetics who take cinnamon bark supplements. The supplement also shows a positive effect on cholesterol levels. A study in rats showed that Pterocarpus marsupium can decrease the blood glucose level of diabetic rats and also improve the weight of the diabetic animals, explains an article in the Indian Journal of Pharmacology, published by the National Institutes of Health.
Although research on these ingredients and others in BioTRUST IC-5 provides evidence that the supplement is effective as a insulin sensitivity optimizer, it does not necessarily follow that BioTRUST IC-5 produces the weight loss results the company promises, notes Consumer Health Digest. Actually, cinnamon bark is known to increase appetite, according to WebMD.