Benefits of phosphatidylserine made from cow brains include improvements in memory, language skills and attention in older people and those with Alzheimer’s disease symptoms, according to WebMD. However, the effects only last for about four months, and patients with milder symptoms derive the greatest benefit, as of 2015.
Cow brains have been the source of the chemical phosphatidylserine for most studies, but supplements primarily use phosphatidylserine obtained from cabbage or soy, notes WebMD. It is unknown whether plant-based phosphatidylserine equals or surpasses the animal-based supplement in its ability to reduce Alzheimer’s disease symptoms. Patients in studies have taken 100 milligrams of phosphatidylserine orally, three times per day, for memory impairment symptoms related to age. Side effects, such as upset stomach and insomnia, may develop with doses over 300 milligrams.