Cetyl myristoleate may help improve knee function and range of motion in osteoarthritis patients when taken orally with fish oil and soy lechitin, as stated by WebMD. Some also claim that it is effective in treating rheumatoid arthritis, psoriasis, emphysema, fibromyalgia, back pain, autoimmune diseases and Reiter's syndrome.
Cetyl myristoleate is part of a group of naturally occurring fatty acids known as cetylated fatty acids, according to WebMD. The substance has gained attention because it occurs in certain mice that are immune to developing arthritis even when researchers attempt to cause it in the lab. Cetyl myristoleate and other cetylated fatty acids may work by softening tissues, lubricating joints and muscles, increasing flexibility, boosting immune function and reducing inflammation. When used for osteoarthritis, cetylated fatty acids are often applied to the skin.
Although no side effects have been reported for short-term use as of 2015, the safety of long-term use of cetyl myristoleate is yet to be determined, as stated by WebMD. Women who are pregnant or nursing should avoid taking the substance. The dosage used for scientific research includes 350 milligrams of the cetylated fatty acid blend Celadrin taken orally six times per day. Researchers have also studied Celadrin applied to the skin twice daily for osteoarthritis.