Benadryl brand products provide relief from itchy skin, which is medically referred to as pruritus. Benadryl's Itch Stopping Topical temporarily alleviates itching and discomfort related to sunburn, minor skin injuries, mild skin irritations, insect bites and skin poisoning, states WebMD.
Individuals who develop pruritus due to an allergic reaction take oral antihistamines, including Benadryl, to relieve itchy skin, notes Mayo Clinic. Benadryl contains the active ingredient diphenhydramine. This chemical functions by inhibiting the activity of histamine in the body to prevent itchy skin from developing.
Patients with pruritis use Benadryl's Itch Stopping Topical by directly applying the cream on the itchy area, typically up to three to four times a day. It is essential to check the product's label prior to application and then to follow directions for use, cautions WebMD.