Bed bug bites typically disappear in one to two weeks. Bites are usually not dangerous and can be treated with over-the-counter anti-itch creams, according to Healthline.
Bed bugs usually bite during the night, leaving a person to discover red and itchy marks in the morning, Healthline explains. The bite appears red and swollen with a dark red center. Bed bug bites are usually grouped together or in a line. There may be blisters or hives at the bite site. Bites can be found anywhere on the body but most commonly occur on areas of the skin that remain exposed during sleep, such as the hands, arms, legs and face. It may take a few days for bite symptoms to show or even be weeks before a person realizes that there is a pattern to the bites; this is because bed bugs do not feed every night.
Bed bug bites are itchy and annoying but usually are not threatening to a person's health, according to Healthline. Anti-itch cream helps with the itching, and an antihistamine reduces irritation and burning. Ice packs are helpful because they numb the skin and reduce the urge to scratch. Scratching bites may cause secondary infection and swelling, which typically benefit from an antiseptic cream or lotion.