The best anti-fungal cream to purchase without a prescription depends on what condition is being treated. Aftate, or the generic tolnaftate, is a medication commonly used for athlete's foot, while Extina, or ketoconazole, is used for dermatitis. A condition must be classified in order to create an individualized treatment plan.
Topical anti-fungal medications are applied directly onto the skin in the affected area needing treatment. There are also several creams, ointments, shampoos and powders used to kill or deactivate fungi and yeast, which are the main sources of fungal conditions. Most medications are topical, but there are also treatments and creams inserted vaginally for conditions such as yeast infections.