What is the best antibiotic for sinusitis?


Quick Answer

The best antibiotic for sinusitis depends on the severity of the infection and what type of medication works best for the patient. Antibiotics prescribed for the treatment of acute sinusitis include amoxicillin, Augmentin, azithromycin, levofloxacin, Levaquin, Bactrim and Septra, according to WebMD. Antibiotics are administered orally in pill form or delivered intravenously, and they work by preventing the growth of sinusitis-causing bacteria.

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Full Answer

Generally, antibiotics are not prescribed as a first-line of defense in treating sinusitis, notes WebMD. It is only when sinusitis symptoms are unresponsive to home treatments, when symptoms become severe, or when complications arise that antibiotics are used.

The first choice of most physicians in treating sinusitis or its complications, including pus that forms in the sinus cavity, is amoxicillin, according to WebMD. Amoxicillin is generally the most effective and comes with the fewest side effects. However, anyone who has a history of mononucleosis or who is allergic to amoxicillin should not use it but should be prescribed trimethoprim-sulfamethoxazole instead.

The course of antibiotic treatment depends on the severity of the sinusitis and the antibiotic prescribed, notes WebMD. If improvement in the condition is not seen within five days, a different antibiotic may be required. Doctors may prescribe other medications alongside the antibiotic, such as medicines that thin the mucus produced by the infection or that improve drainage of the sinuses.

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