Over-the-counter, non-steroidal anti-inflammatory drugs to treat back pain include Advil, Aleve and Motrin, according to About.com. Prescription anti-inflammatory drugs for back pain include Celebrex and Relafen. Aspirin is also an effective anti-inflammatory analgesic medicine to reduce back pain.
Non-steroidal anti-inflammatory medications decrease prostaglandin production to reduce back pain, says About.com. Doctors typically recommend non-steroidal anti-inflammatory medications for acute or chronic back pain, which can be caused by poor posture, pregnancy, obesity, scoliosis and other conditions, according to Mayo Clinic. Severe, unrelenting back pain may be treated with oral steroids or steroid injections. Surgery to treat back pain is almost always a last resort.