What Is Anteroseptal Myocardial Damage?

Anteroseptal myocardial damage is tissue damage to the anterior (front) part of the heart, right in front of the muscular wall separating the left and right sides of the heart. This damage is usually caused by a myocardial infarction, better known as a heart attack, the journal Cardiovascular Research reports.

An infarct is a region of dead tissue resulting from blocked or insufficient blood flow to a region. When all or part of the left anterior descending, or LAD, coronary artery is blocked, the energy-hungry muscle toward the front of the heart, including the anteroseptal region, can die. This dead muscle is eventually replaced with scar tissue, according to Cardiovascular Research. Anteroseptal damage can be the result of a smaller acute infarct or a large blockage of the entire LAD.

Anteroseptal damage is medically significant because it affects how the heart pumps blood. This damage causes an alteration of the heart beat, and the ECG Learning Center reports that this damage can be diagnosed by its distinctive electrocardiogram, or ECG, pattern. Due to the size of the area affected by the LAD, complete anterior infarctions reduce cardiac output by as much as 50 percent and lead to poor medical outcomes, Life in the Fastlane reports. Damage focused on the anteroseptal region alone is more limited in scope and has a better medical prognosis.