Angioneurotic edema, also called hereditary angioedema, is a disorder that repeatedly causes tissue swelling, abdominal pain and swelling of the larynx, which can restrict breathing, states MedicineNet.com. Patients are born without C1 esterase inhibitor, a protein that ordinarily stops rapid swelling under the skin. Treatments include antihistamines and male steroids.
The U.S. Food and Drug Administration has approved Ruconest, a recombinant C1 esterase inhibitor, to treat angioneurotic edema attacks in adolescents and adults, according to Medscape. Ruconest brings relief to areas of the body affected by angioneurotic edema, such as the face, arms, hands, legs, buttocks and genitals. Patients suffering an attack may also experience swelling of their intestines, stomach and bladder combined with vomiting or diarrhea. When swelling of the tongue and upper airway occur, it can lead to asphyxiation in rare cases.