Aleve's side effects on the kidneys include cloudy urine, decreased urine output and end-stage kidney failure in some patients, warns Drugs.com. Kidney failure due to the medication is more likely in patients who exhibit hypersensitivity to the medication.
Aleve is a brand name for the drug naproxen, according to Drugs.com. Kidney function problems due to Aleve's side effects are more severe in patients with complications such as heart failure, advancing age or use of diuretics.
Aleve causes side effects with other systems in the body as well, reports Drugs.com. It can affect the digestive tract, causing stomach upset, constipation, bleeding or peptic ulcers. Aleve causes liver problems in some patients, and naproxen-induced hepatitis is responsible for the death of some users. Aleve causes heart palpitations and elevated blood pressure in some users. Other side effects include ringing in the ears and altered hearing.
Aleve is a nonsteroidal anti-inflammatory drug, explains Drugs.com. Patients use it and other NSAID medications to temporarily treat pain and inflammation. Common uses for Aleve include treating arthritis, menstrual cramps, headaches and muscular aches. It is also a temporary fever reducer. Long-term use of naproxen is more likely to cause side effects. Patients who take more than 5,000 pills containing NSAIDs during their lifetime have a greater chance of end-stage renal failure.