The American Cancer Society recommends starting prostate-specific antigen screening at age 50, notes Mayo Clinic. Men with a higher risk of prostate cancer should be regularly tested, starting at age 40 or 45.
The American Urological Association disagrees, and it recommends against PSA screening for men ages 40 to 54 with an average risk of cancer, according to Mayo Clinic. The AUA advocates an initial baseline PSA screening at age 40 followed by shared decision-making between the doctor and patient about when to screen between ages 55 to 69. Routine screening past the age of 70 has been shown to be less beneficial and is not recommended by the AUA.