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What are the adverse reactions of the DPT vaccine?

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Quick Answer

Fever along with redness and soreness at the injection site are the most common adverse side effects of the diphtheria, tetanus and acellular pertussis vaccine, according to the Centers for Disease Control and Prevention. These are considered mild adverse side effects.

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Full Answer

Tiredness, fussiness and vomiting are mild side effects of the diphtheria, tetanus and acellular pertussis vaccine, explains the Centers for Disease Control and Prevention. Moderate problems that may occur following this vaccine include seizure, non-stop crying for more than three hours, and a fever higher than 105 degrees Fahrenheit. Seizures occur in about one in 14,000 children, non-stop crying occurs in about one in 1,000, and high fever occurs in about one in 16,000 children.

Serious adverse side effects occur in about one in a million children, states the Centers for Disease Control and Prevention. These include coma, long-term seizures and permanent brain damage; however, these side effects are so rare, they may be caused by other conditions. In any case, when considering the side effects of the diphtheria, tetanus and acellular pertussis vaccine, it is important to monitor the child for fever. It is recommended to give a child an aspirin-free pain reliever following the injection for up to 24 hours to combat fever and pain.

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