There are two large cities called Manchester. One is a city in England, and the other is a city in the state of New Hampshire.
Manchester is located in northwestern England, whereas Manchester, N.H. is located in the southern portion of New Hampshire. Manchester, N.H. is the largest city in the northern New England area, which includes Maine, Vermont and New Hampshire. Manchester, England is part of the second most highly populated urban area in the entire United Kingdom. As of 2014, the population of Manchester in England is 502,900, whereas the population of Manchester in New Hampshire is only 109,565.