What Are Some Major U.S. Cities?

Five major U.S. cities by population and rank are New York City, Los Angeles, Houston, Chicago and Philadelphia. The U.S. Census reported in May 2015 that 10 cities have 1 million or more people. Besides the top five, the others are Phoenix, San Antonio, San Diego, Dallas and San Jose.

New York is a top leader in finance, communications and the arts; it is the U.S. center for advertising and fashion. The United Nations and the headquarters of many major corporations are in New York.

Los Angeles is known for its citrus industry, its major port, and its film and entertainment industry. Los Angeles County has the largest manufacturing area in the United States. The city is a hub for international trade and wholesalers in apparel, textiles, jewelry and toys.

Houston, another major port city, is known for its oil and natural gas industry and also for aerospace. It is a major center for business, finance, science and technology.

Chicago is a port city for the Great Lakes. It is the Midwest's commercial and cultural center.

Philadelphia is known historically as the site of the founding of the United States at Independence Hall, but today the city is a leader in health services, insurance, pharmaceutical manufacturing and engineering. The city's harbor is a major shipping center.