As of 2010, the largest city in California by population is Los Angeles with a population of 4,094,764. The second-largest city in California is San Diego, followed by San Jose, San Francisco and Fresno third, fourth, and fifth respectively.
In terms of land area, Los Angeles is the largest city in California at 468.7 square miles. San Diego is the second largest with an area of 325.2 square miles. The next largest cities in California by area are California City, San Jose and Bakersfield. Despite being the fourth-largest city in California by population, San Francisco is not among the 25-largest cities in California by land area.