Interesting facts about Huntingdon, Pennsylvania, include that Budget Travel magazine named Huntingdon the fifth coolest small town in the United States in 2009, the Reverend Dr. William Smith founded the borough on Native American council ground, and the borough is named for Selina, Duchess of Huntingdon in England. The town's original name was Standing Stone in honor of the ancient Standing Stone Monument that settlers found in the area.
Residents replaced many of Huntingdon's original buildings between the Civil War and World War I. The borough gained 50 new buildings downtown between 1865 and 1915. New railroad transportation helped the borough's population grow from less than 1,500 residents in 1850 to over 6,000 in 1900, spurring the downtown development. The Huntington Borough Historic District has been on the National Register of Historic Places since 1986.
Huntingdon is located on the Juniata River in a fruit-growing agricultural area of Pennsylvania. The land also provides iron, clay, limestone and fire clay. Timber from the surrounding forests provides material for the borough's furniture manufacturers and lumber plants.
Hurricane Agnes flooded the borough in 1972, and Hurricane Ivan flooded it again in 2004. The second hurricane closed all roads out of town except the road to the top of Stone Ridge Creek.