The Hotel Melia Cayo Santa Maria is located in Cuba, about 0.3 miles from Sol Cayo Santa Maria and 6 miles from the Las Brujas Airport. The resort features a Cuban Caribbean environment.
An international guest to the resort is required to have a passport and visa if the guest's home country is not exempt from acquiring a visa. Visitors are asked to pay for services in Cuban convertible pesos. In some areas, including Cayo Santa Maria, the euro is accepted. The U.S. dollar is not considered a valid form of currency, and debit or credit cards issued by U.S. banks are not accepted.