While definitive findings concerning sucralose side effects remain unknown, as of 2015, research links ingestion of this artificial sweetener to metabolic syndrome, according to the American Diabetes Association. Metabolic syndrome causes excess build-up of fat around the midsection, a spike in bad cholesterol that remains high, consistent high blood pressure and high blood sugar levels, states HealthResearchFunding.org. Other reported side effects include migraines, feelings of vertigo, nausea and allergic reactions.Continue Reading
In 2013, the Center for Science in the Public Interest removed the "Safe" label from sucralose, replacing it with a "Caution" label due to research linking sucralose ingestion to leukemia in mice, states the CSPI. Further review is necessary before the group determines if sucralose is safe to include in food, as of 2015. This study, conducted by Dr. Morando Soffritti, director of the Ramazzini Institute in Bologna, Italy, found a lifetime of sucralose consumption linked to an increase risk of leukemia, explains Medical News Today.
The U.S. Food and Drug Administration continues to label sucralose, marketed as Splenda, as safe, states the FDA. However, research links the sweetener to lower levels of healthy gut bacteria, states HealthResearchFunding.org. Ingesting sucralose can lower these levels by as much as 50 percent. This, in turn, causes higher P-glycoprotein levels, which interferes with medications and medical treatments for those with severe health conditions, such as cancer or heart disease.Learn more about Dry Ingredients