There is no scientific evidence that links artificial sweeteners such as Equal to unwanted side effects or serious health concerns, according to the Mayo Clinic. Artificial sweeteners have been the subject of various research studies since the 1970's, and have been deemed safe in limited quantities.
Artificial sweeteners remain controversial, largely based on rumored links to cancer, notes the Mayo Clinic. However, the study that sparked said rumors in the 1970's, which linked artificial sweeteners to cancer in laboratory rats, has been disproved time and time again. In fact, the U.S. Food and Drug Administration re-evaluated the safety of aspartame, the sweetening agent in Equal, in 2007, according to ABC News. Over 200 studies were reviewed, and no evidence was found to indicate negative side effects. Governments worldwide have repeatedly deemed aspartame safe in moderation.
The FDA has established an acceptable daily intake, or ADI, for artificial sweeteners, explains the Mayo Clinic. ADI's are considered the largest amount safe to consume in a day. The amount is an estimated 100 times less than the smallest amount that could cause negative side effects or health concerns. While accusations against artificial sweeteners abound on the Internet, there is no verified scientific evidence in support of such claims.