A single shot of 80-proof plain vodka, which is 1.5 ounces, contains approximately 97 calories and no significant nutritional value, while a single shot of 100-proof plain vodka contains approximately 123 calories. Flavored vodkas, which contain added sugars and fruits, range from 69 to 125 calories per single shot.
Flavored vodkas made with fruit, herb and spice extracts may also contain carbohydrates and sodium, depending on the manufacturer's recipe. Adding mixers, such as soda, milk or fruit juice, increases the calorie, fat and carbohydrate content. Vodka can be made from fermented grains, including corn, rye, soybeans or wheat. Vodka is also made with beets, grapes, potatoes or rice.