A spiral-cut ham needs to cook for 10 to 18 minutes per pound, depending on oven temperature. A 5-pound ham needs a minimum of 50 minutes in the oven at 275 degrees Fahrenheit.
To make a delicious spiral-cut ham without drying out the meat, place the ham in a roasting pan and cover the pan tightly with foil or a lid. Bake the ham at 275 F for the required time. Overheating the ham results in dry meat, so it's best to start with less time and add more only until the meat is warmed through. Glazing, if desired, should be done 10 minutes before the recommended cooking time is up.