In 2011, the most popular menu item at the Frederick, Maryland Jersey Mike's according to manager Greg Mazzuca was the Original Italian Sub. The sub is number 13 on the menu and contains provolone, ham, prosciuttini, cappacuolo, salami and pepperoni.
Another Jersey Mike's menu favorite is the Jersey Shore's Favorite Sub. It contains provolone, ham and cappacuolo. Many customers recommend ordering it "Mike's Way": with onion, lettuce, tomatoes, red wine vinegar, olive oil blend and spices.
The Baja Chicken Wrap is a popular menu option that is not a sub. It consists of grilled sliced chicken breast, melted cheese, salsa, lettuce and jalapeno peppers wrapped in a warm wheat or flour tortilla. The dessert menu's cookies are popular items as well.