A good recipe for blackened tilapia is Big Daddy's blackened tilapia from the Food Network. The blackening mixture consists of paprika, thyme, oregano, garlic powder and onion powder, as well as salt and pepper.
Mix together the blackening spice in a small bowl by starting with 3 tablespoons of smoked paprika, 1 tablespoon of onion powder, 1 teaspoon of dried ground thyme, 1 teaspoon of dried oregano and 1/2 teaspoon of garlic powder. Season the mixture with 1 teaspoon of salt, 1 teaspoon of ground black pepper and 1 teaspoon of cayenne pepper. Dredge 4 tilapia fillets in the blackening spice, and cook them in a skillet with 2 tablespoons of grapeseed oil at medium high heat for two to three minutes on each side. Squeeze fresh lemon juice over the fish before serving.
Another good recipe for blackened tilapia calls for a blackening spice made from 1 1/2 teaspoons of paprika, 1 1/2 teaspoons of brown sugar, 1 teaspoon of dried oregano, 3/4 teaspoon of garlic powder and 1/2 teaspoon of ground cumin. Stir in 1/2 teaspoon of salt and 1/4 teaspoon of ground red pepper, and rub the spice mixture over 4 tilapia fillets. Cook the fillets in a cast-iron skillet at medium heat with 1 tablespoon of canola oil. After three minutes, flip the fillets and cook them for another three minutes.