Pomegranate juice was found to both reverse and prevent clogged arteries in a 2005 study cited by WebMD. The juice's high antioxidant levels stimulate the production of a chemical that helps to keep arteries open and allow blood to flow through them more efficiently.
Atherosclerosis, or hardening of the arteries, occurs when cholesterol and other waste materials build up inside arteries, causing them to narrow and harden. Blood can no longer circulate efficiently, which puts strain on the heart. Mayo Clinic reports that the antioxidants found in pomegranate juice can decrease the levels of low-density lipoprotein, or LDL, cholesterol. Harvard Men's Health Watch states pomegranate juice can prevent oxidative damage to LDL cholesterol. This occurs when oxygen levels are too high for the metabolism to process, resulting in the production of dangerous by-products called free radicals.
Researchers found that pomegranate juice contained more antioxidants than red wine and all other fruit juices. When blood vessel cells were exposed to physical stress like that experienced in high blood pressure, the application of pomegranate juice to the stressed cells resulted in significantly less damage. Mayo Clinic suggests that consumers purchase only pure pomegranate juice and avoid products that contain additional fruit juices and sugars.