According to doctors at Med-Health.com, consuming large amounts of Gatorade can cause serious medical side effects. Gatorade is meant to provide hydration and electrolytes in small to moderate amounts.
Med-Health states that a 32 ounce serving of Gatorade contains about 200 calories, so ingesting too much could lead to weight gain. The product also has enhanced vitamins and minerals, such as vitamin A, and fat-soluble vitamins, which should not be consumed in excess. Overconsumption of these substances could lead to vitamin toxicity. Additionally, hyponatremia is a fatal side effect caused by excessive hydration of cells causing very low sodium levels in the body, which could occur after too much Gatorade. Furthermore, excessive Gatorade intake paired with poor diets or medical conditions could lead to hypertension or high blood sugar.