The Betty Crocker apple coffee cake recipe that uses Bisquick mix is Apple Coffee Cake, a recipe that calls for Bisquick mix in both the cake and the streusel topping. Betty Crocker also offers a range of Bisquick coffee cakes that don't contain apples, such as Blueberry Cinnamon Coffeecake and Chocolate-Cream Cheese Coffee Cake.
To make Apple Coffee Cake, combine 2 cups of Bisquick mix, 2/3 cup of milk, 3 tablespoons of granulated sugar and 1 egg. Once the ingredients are well mixed, pour half of the batter into a greased square pan, and layer on 2 peeled and thinly sliced apples. To make the streusel, add 2/3 cup of Bisquick mix with 1 teaspoon of ground cinnamon, 1/2 teaspoon of ground nutmeg and 2/3 cup of packed brown sugar, and cut in 1/4 cup of cold butter until the mixture is crumbly. Sprinkle half of this mixture over the sliced apples in the pan, and pour the rest of the coffee cake batter over the apples.
Top the batter with the rest of the streusel mixture and 2 tablespoons of chopped nuts. Bake the cake at 400 degrees Fahrenheit for 25 minutes, and allow the cake to cook for 20 minutes in the pan. Drizzle a glaze made from 1/2 cup of powdered sugar and 3 teaspoons of milk over the cake while it's still warm.