Cover catfish fillets with spices or sauce, then bake them in the oven until they are cooked through. Alternatively, coat fillets with bread crumbs and seasonings before baking them in the oven.
To bake catfish according to one of the recipes by The Catfish Institute, begin by making a spice rub. Combine paprika, cayenne pepper, onion powder and garlic powder. Add dried thyme, dried oregano, salt and pepper. Mix all ingredients thoroughly. Coat catfish fillets with a little olive oil and rub the spice mix into the flesh. Place a piece of oiled aluminum foil in a sheet pan. Arrange the fillets on the foil, then bake at 375 degrees Fahrenheit for 15 to 20 minutes or until their crusts turn a deep golden brown.
A baked catfish recipe on FoodNetwork.com starts by seasoning the catfish fillets with salt and pepper, then placing them in a casserole dish. Simmer butter, dry white wine, lemon juice, chopped garlic and chopped cilantro to make a sauce, then pour this over the fish and scatter paprika on top. Bake the fish at 375 degrees Fahrenheit for 10 to 12 minutes or until the flesh is thoroughly cooked.
A simple baked catfish recipe on About.com involves marinating catfish fillets in lemon juice, applesauce, egg white and vegetable oil before coating them in seasoned bread crumbs. Bake the fish at 400 degrees Fahrenheit for approximately 20 minutes or until the flesh is flaky.