Some types of alcohol do expire even when they are not opened, according to the Nova Scotia Liquor Corporation. Liquors that have sugar or cream added tend to have a shorter shelf life.
Bourbon, rum, scotch, vodka and whiskey typically last for several years even if they are opened, according to the NSLC. This is a result of the high alcohol content of these liquors. Liquors that include cream sometimes curdle after just a few months if the bottles are kept in a warm storage area. Wine starts to oxidize once it is opened, which does not cause the wine to expire although it sometimes affects the taste.