MLA does not offer specific formatting instructions for an epigraph, so writers are encouraged to follow other MLA rules and indent 2 inches from the edge of the paper. Spacing and placement of the epigraph is a stylistic choice that is left up to the individual writer.
Epigraphs inserted into a smaller work, such as an essay, are typically single-spaced so they do not take up too much room in the essay. Optionally, writers may make the font size for the epigraph slightly smaller or italicize it to help it stand out. If the epigraph precedes a longer work, such as a novel, the writer may choose to place the epigraph on its own page after the title page.