According to The Statistics Portal, total toothpaste sales in the United States amounted to about $1.6 billion for 2011 and 2012. Toothpaste sales via drug outlets in the United States amounted to $517.2 million.
The Statistics Portal states that Proctor and Gamble is the largest vendor of toothpaste in the United States. Proctor and Gamble sells the toothpaste brand Crest and attributes the most revenue from this product type. In 2012, $192 million was spent on advertising for Crest alone. Due to the vast amount of money spent on advertising, Crest is one of the highest selling products in personal care brands with the largest advertising budget in the United States.