Kleenex tissues are made by mixing wood pulp with water, straining out the cellulose fibers and removing the water to form fiber sheets. These sheets are dried and pressed on a cylinder, then removed from the cylinder and layered into two- or three-ply stacks.
The tissue paper used for Kleenex was first intended for Kotex feminine hygiene products by the Kimberly-Clarke manufacturer in the 1920's. Unpopularity of Kotex at the time caused the company to change its formula slightly and market the product as a disposable cleansing tissue. In 1930, Kleenex became a popular substitute for the handkerchief, eliminating the need for laundering handkerchiefs and providing an inexpensive alternative.