How Do You Activate a MasterCard?

Activate your MasterCard by calling the telephone number on the activation sticker on the card's back or by using your personal identification number at any automatic teller machine, according to Santander Bank. Making a purchase using the card and the PIN also activates the card.

Contact an advisor between 7 a.m. and 8 p.m. any day of the week, except federal holidays, to activate your card, explains Santander Bank. If you hold a PayPal Prepaid MasterCard, activate it online at Activate the card by going to the Activate page, entering your 16-digit card prepaid card number and clicking on the Activate Card button, according to PayPal. You must activate your card before making purchases or adding money.