Over-the-counter pain relievers work well in relieving discomfort caused by tattooing, according to WebMD. However, it is important to contact a health care provider if any signs of infection, such as redness and swelling, or signs of an allergic reaction develop.
The experts at WebMD recommend the use of any one of several non-prescription pain medications, including acetaminophen, which is most commonly branded as Tylenol. Aspirin, including brands like Bufferin and Bayer, is another effective pain reliever. Other drugs effective in relieving tattoo pain include ibuprofen, which is branded as Advil and Motrin, and naproxen, with brand names that include Aleve and Naprosyn.