A lizard tattoo is a sign of good fortune and wealth. The symbol of abundance or wealth in Egyptian hieroglyphics is also shaped like a lizard.
In some areas of West Africa, an image of a lizard is painted on the outside of homes to keep evil away and welcome happiness and peace into the house. The term "lizard brain" is used to describe someone who has a keen sense of awareness, follows his intuition and does what is necessary to survive. Since lizards move very quickly, a tattoo of a lizard can also be a sign of agility and speed.