Rue 21 sells dresses, tops, pants, shorts, and skirts. It also sells outerwear, swimwear, active wear and lingerie. The retail chain offers both regular sizes and plus sizes for girls.
Rue 21 offers girls' tops, jackets, and dresses in sizes XS to XL as well as a plus size section that includes sizes 1XL to 3XL. Sizes in girls' pants, denim, skirts, and shorts range from 0 to 13/14 and sizes 14 to 24 in the plus size section. The store also sells shoes and accessories such as jewelry and beauty products.
As of 2015, some of the store's trend collections include American Summer, Deep in Space, Summer Blues, Boho Beats, and Emoji.
The American Summer collection features summer clothing, such as shorts, tanks, dresses and swimwear, with American flag graphics. The Deep in Space collection features apparel such as leggings and graphic tees with bright interstellar and galactic prints. The Summer Blues collection features swimwear, sandals, flip flops, water bottles, sun hats, and other summer apparel. The Boho Beats collection features luxe bohemian apparel such as peasant tops, maxi skirts and dresses, and flare jeans. The Emoji collection features graphic tees and accessories with popular emoticon images such as smiley faces and food images.