Hydroderm contains collagen, which is known to naturally decrease with aging, meaning that the product could possibly work against the aging and wrinkling of skin by restoring collagen to skin. However, no clinical studies are publicly available that attest to the effectiveness of the product as of May 2015.
As with most skin products that claim to be age-defying, the only real evidence of Hydroderm's efficacy is anecdotal. The marketing materials of the popular wrinkle serum make strong claims as to its ability to remove the effects of aging on the skin. However, no actual clinical results are offered to support these claims. Additionally, the company recommends that the serum should be used in conjunction with other Hydroderm products.