Garlic is one of the best home remedies to get rid of a pimple quickly. The high sulfur content decreases the amount of time it takes for the antiseptic and antiviral properties of the garlic to work. Cut a bulb and rub the cut side on the pimple.
Another good way to get rid of a pimple overnight is to use ice. Wrap a few ice cubes in a cloth. Placing them on the pimple will reduce inflammation and force the trapped dirt and sebum out. A third method is to make a paste of lemon juice and baking soda. Apply it to the pimple. Wash it off after a few minutes to keep the skin from drying out.