Some prescription acne drugs have been linked to deaths. Accutane has been linked to multiple deaths due to suicide. Diane-35 is tied to a number of deaths due to blood clots. Minocycline hydrochloride has caused at least one death.
Accutane is a retinoid. Its use increases the risk of depression and suicidal behavior in some people. It causes severe birth defects if taken during pregnancy.
Diane-35 is a hormone preparation known to increase the risk of blood clots.
Minocycline hydrochloride is an antibiotic. It is generally believed to be safe, but any medication can cause allergic reactions in rare individuals.