Caring for a nose piercing includes not touching the piercing with dirty hands. It's also advisable to wash the piercing with a solution of salt and water.
The Nose Rings Guide suggests washing a piercing two or three times each day. Saline solutions can be found at the local drugstore, or a solution can be made at home with sea salt and boiling water. Cotton balls can be used to clean the piercing. It's also best to avoid putting cosmetics directly on the piercing, so the makeup will not get into the hole. Waiting until a piercing has healed completely before taking the nose ring out and replacing it with a new one is recommended.