As of 2015, there is decent scientific evidence that taking CoQ10 is beneficial in the treatment of high blood pressure and chronic heart failure, according to Mayo Clinic. There is very strong scientific evidence that supplementation and increasing dietary intake of the coenzyme helps correct a CoQ10 deficiency.
A deficiency of coenzyme Q10, or CoQ10, can cause health problems including chest pain, heart failure and high blood pressure, notes Mayo Clinic. The human body naturally produces CoQ10, but supplementation may be necessary in the case of deficiency due to disease or inadequate dietary intake. Diseases that can contribute to CoQ10 deficiency include cancer, diabetes, Parkinson's disease and HIV/AIDS. A deficiency can also result if the body uses an unusually high amount of CoQ10.
There is unclear scientific evidence of the benefits of taking CoQ10 for a wide array of health purposes, explains Mayo Clinic. There have been studies demonstrating skin wrinkles may improve when people take CoQ10 in combination with other antioxidants and minerals. However, additional research is necessary to determine the extent to which CoQ10 plays a role in skin aging. Evidence suggests idebenone, a man-made substance similar to CoQ10, is useful in treating Alzheimer's disease, but there is insufficient evidence CoQ10 itself offers any benefit to Alzheimer's patients.