At his website, Tyler Perry does have a section dedicated to writing to his fans. You can sign up for his newsletter and receive messages from him.
Diving more into his blog, it does look like you can communicate to him by leaving comments. There are several blog posts where Tyler Perry has responded to a fan's comment. He also has a Talk to Me section on his website where fans interact in a forum daily. The website seems to be the best chance to communicate with Tyler Perry, and signing up to receive personal emails from Tyler Perry only takes a moment to do. Just click Subscribe on the My Message page and fill in your information.