"The Wendy Williams Show" contains many segments such as the Hot Talk panel, the Hot Seat, and Ask Wendy. The most well known and popular segment on the show is her 20-minute Hot Topics show opener.
The segments presented on the show vary each day and are sometimes influenced by the show's guests. Some segments are geared toward fashion, sometimes giving a makeover to a viewer. On another day a cooking demonstration might occur. Due to the show's typical focus on gossip and celebrity news, celeb bloggers and journalists are often brought on to discuss recent events in pop culture. A daily segment called the After Show is hosted exclusively online on Wendy's YouTube channel.