The second season of "Royal Pains" consisted of 18 episodes. The first episode, "Spacicity," aired on June 3, 2010, and the finale, "Listen to the Music," aired on Feb. 24, 2011.
Other episodes in the second season of "Royal Pains" include "Keeping the Faith," "Whole Lotto Love" and "A History of Violins." Main cast members of the second season included Mark Feuerstein, Paulo Costanzo, Jill Flint and Reshma Shetty. The second season also featured a number of guest stars, such as Marcia Gay Harden, Campbell Scott and Ezra Miller. Other second-season guest stars include Anasatsia Griffith, Peter Strauss and Tom Cavanagh.