One example of foreshadowing in "Of Mice and Men" is in the beginning, when Lennie is holding and stroking a dead mouse. This scene is foreshadowing the climatic event near the end of the novel, when Lennie accidentally kills Curley's wife. "Of Mice and Men" is full of foreshadowing of this event.
Other instances foreshadowing the climax of the book are found when Lennie receives a puppy from Slim. He accidentally kills this puppy the same way he killed the mouse, by stroking it too firmly. From these parts of the story, the reader learns that Lennie is simple and is not aware of his own strength. The reader also learns that Lennie does not mean any harm. Also, at the beginning of the book, the reader learns that Lennie and George were run out of the previous town they lived in because Lennie was accused of attempted rape, a misunderstanding which arose when Lennie was touching the soft fabric of a girl's dress and did not release the dress when asked. All of these scenes remind the reader that Lennie enjoys touching soft things. When Curley's wife offers to let Lennie touch her hair near the end of the book, he again gets overexcited, which scares the woman and leads to her accidental death at Lennie's hands.