According to the IRS, you may not deduct mileage for commuting to your regular place of work from your home address if you are a W-2 employee. If you are classified as an independent contractor and run your own business then there are several tax advantages regarding your automobile as a business expense. You may choose either the actual expense method or standard mileage deduction method.
. More detailed information is available at http://www.irs.gov/newsroom/article/0,,id=163780,00.html.