• Hesperus, Latinized form of Hesperos, a Greek mythological figure (Roman Vesper)
• Vesper Lynd, a fictional character of Ian Fleming's James Bond novel Casino Royale
• Vesper, Saskatchewan, formerly a village southwest of Swift Current, Saskatchewan, now abandoned. No buildings remain.
• Vesper (cocktail), a martini-style alcoholic beverage recipe created by Ian Fleming
• Vesper or shaken, not stirred, a manner in which to prepare a martini, as described in Ian Fleming's James Bond novel Casino Royale
• Vesper mission, a planned Venus chemistry and dynamics orbiter of the NASA Discovery Program, to be managed by NASA's Goddard Space Flight Center
• Vesper the name of two, short comic book series published by Acetylene Comis.
• Vesper, Wisconsin, USA, village with population of 527 located in the center of the state.
• A fictional town in the Ultima video game series.
• VSEPR theory in chemistry, often pronounced "Vesper" which is easier to say.

See also Vespers.