Usual_interstitial_pneumonia

Usual interstitial pneumonia

Usual interstitial pneumonia, commonly abbreviated UIP, is the name of a histopathological pattern seen in diffuse lung diseases. Diffuse lung diseases are also referred to as interstitial lung diseases.

UIP is a type of idiopathic interstitial pneumonia. Sometimes, confusingly, it is used as a synoym for idiopathic pulmonary fibrosis.

Differential diagnosis

UIP is seen in:

Histologic appearance

UIP is characterized by:

  • interstitial inflammation,
  • fibroblast foci,
  • (microscopic) honeycombing and
  • patchy lesional distribution (heterogeneous areas of abnormal and normal lung).

History and application of term

UIP, as a term, first appeared in the pathology literature. It was coined by Averill Abraham Liebow.

It is sometimes, confusingly, used to refer to idiopathic pulmonary fibrosis, one of its many clinical correlates.

Pneumonia misnomer?

The definition of "pneumonia" is often described as a '... lung inflammation caused by a virus, bacteria or irritant.'

Etymologically, the usage of "pneumonia" in UIP is correct; the word "pneumonia" is derived from "pneumon" (lung) and the suffix "-ia" (condition).

See also

References

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