Usual interstitial pneumonia
, commonly abbreviated UIP
, is the name of a histopathological
pattern seen in diffuse lung diseases
. Diffuse lung diseases are also referred to as interstitial lung diseases
UIP is a type of idiopathic interstitial pneumonia. Sometimes, confusingly, it is used as a synoym for idiopathic pulmonary fibrosis.
UIP is seen in:
UIP is characterized by:
- interstitial inflammation,
- fibroblast foci,
- (microscopic) honeycombing and
- patchy lesional distribution (heterogeneous areas of abnormal and normal lung).
History and application of term
UIP, as a term, first appeared in the pathology
literature. It was coined by Averill Abraham Liebow
It is sometimes, confusingly, used to refer to idiopathic pulmonary fibrosis, one of its many clinical correlates.
The definition of "pneumonia" is often described as a '... lung inflammation
caused by a virus
Etymologically, the usage of "pneumonia" in UIP is correct; the word "pneumonia" is derived from "pneumon" (lung) and the suffix "-ia" (condition).